The LIP5 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to VTA1. This antibody recognizes Mouse, and Rat antigen. The LIP5 Polyclonal Antibody has been validated for the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding